Intramuscular Quinine in Malaria
نویسنده
چکیده
To the Editor, The Indian Medical Gazette. Sir,?Having read the letter by Dr. D. M. Vasavada in your issue for October 1930 on intravenous quinine, j. am prompted to write to you to emphasise the value o intramuscular injections of quinine in malaria. TllC intramuscular injection is not followed by the fall i11 blood-pressure which occurs with intravenous injeC" lions, the method is easy and safe, whilst the absorption of the drug is slower and its effects more lasting tha0 by the intravenous route. .
منابع مشابه
Intramuscular loading dose of quinine for falciparum malaria: pharmacokinetics and toxicity.
In a study of intramuscular injection of quinine eight adults with moderately severe falciparum malaria resistant to chloroquine were treated with quinine dihydrochloride, being given a loading dose of 20 mg salt (16.7 mg base)/kg followed by three or four eight hourly maintenance doses of 10 mg salt (8.3 mg base)/kg injected into the anterior thigh. All patients responded to treatment. Fever a...
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BACKGROUND In children with falciparum malaria, a proprietary quinine preparation (adjusted to make it less acidic) administered rectally may be easier to use and less painful than intramuscular or intravenous administration. However, rectal quinine may be less effective. OBJECTIVES To compare intrarectal quinine with intravenous or intramuscular quinine for treating malaria caused by Plasmod...
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